WITHDRAWN: Pax genes during neural development and their potential role in neuroregeneration.
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منابع مشابه
Pax Proteins in Embryogenesis and Their Role in Nervous System Development
The mammalian Pax genes encode a family of transcription factors, which play important roles in embryonic development and organogenesis. During the central nervous system development Pax genes have substantial roles in neural differentiation and regional specification. Pax proteins are expressed in populations of nerve cells within the developing forebrain, midbrain, hindbrain and spinal cord. ...
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The paired box genes are a family of nine developmental control genes, which in human beings (PAX) and mice (Pax) encode nuclear transcription factors. The temporal and spatial expressions of these highly conserved genes are tightly regulated during foetal development including organogenesis. PAX/Pax genes are switched off during the terminal differentiation of most structures. Specific mutatio...
متن کاملPax genes in development.
The Pax gene family consists of nine members encoding nuclear transcription factors. Their temporally and spatially restricted expression pattern during embryogenesis suggests that they may play a key role during embryogenesis. Direct evidence for the important role of the Pax genes during embryonic development has been demonstrated by the correlation of mouse developmental mutants and human sy...
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In a theoretical model of morphogenesis, Atchley and Hall (Atchley and Hall, 1991) proposed cell condensation, the aggregation of like cells, as the basic unit from which morphology is constructed during development. Indeed, cell condensation is an early developmental process in essentially every organ during vertebrate embryogenesis (Thesleff et al., 1995). Likewise, transformations between th...
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Members of the paired box (Pax) gene family are expressed in discrete regions of the developing central nervous system, suggesting a role in neural patterning. In this study, we describe the isolation of the chicken homologues of Pax-3 and Pax-6. Both genes are very highly conserved and share extensive homology with the mouse Pax-3 and Pax-6 genes. Pax-3 is expressed in the primitive streak and...
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ورودعنوان ژورنال:
- Progress in neurobiology
دوره 95 3 شماره
صفحات -
تاریخ انتشار 2011